The West Coast will face a new set of travel restrictions from Thursday, CNN affiliate WWL reports.
Travelers are being asked to limit their trips to the entire region and will be required to obtain a state license.
Travel to California, Oregon, Washington and Idaho is still permitted, but visitors from Hawaii, Alaska, the Virgin Islands and Puerto Rico will be asked to obtain licenses.
“We’re going to make sure that travelers are aware of the restrictions that are coming, that you should exercise caution,” Homeland Security Secretary Jeh Johnson said on CNN’s “New Day.”
The restrictions come amid an ongoing opioid epidemic in the United States, which has claimed at least 33,000 lives.
The latest data released Monday by the Centers for Disease Control and Prevention show the rate of overdose deaths among Americans has jumped more than 25% since January.
More than 10,500 people have died from opioid overdoses since January, according to the CDC.
The Centers for Medicare and Medicaid Services has said it will waive some of the regulations until the crisis has been resolved.
Some states also have moved to reinstate their restrictions.
“It’s not clear why this is happening, and it’s not a good idea to try to make the situation worse,” Johnson said.
Johnson also said that the new rules are “unlikely to change the situation.”